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Buy Lion’s mane magic mushroom online. Lion’s mane mushrooms are large, white, mushrooms that resemble a lion’s mane as they grow. They contain bioactive substances that have many beneficial effects on the body, especially the brain, heart, and gut. Lion’s mane mushrooms, also known as hou tou gu or yamabushitake, have both culinary and medicinal uses in Asian countries like China, India, Japan, and Korea.
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Here are nine health benefits of lion’s mane mushrooms and their extracts, along with dosages, preparation, and side effects.
The brain’s ability to grow and form new connections typically declines with age, which may explain why mental functioning worsens in many older adults.
Studies have found that lion’s mane mushrooms contain two special compounds that can stimulate the growth of brain cells: hericenones and erinacines.
Additionally, animal studies have found that lion’s mane may help protect against Alzheimer’s disease, a degenerative brain disease that causes progressive memory loss.
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In fact, lion’s mane mushroom and its extracts have been shown to reduce symptoms of memory loss in mice, as well as prevent neuronal damage caused by amyloid-beta plaques, which accumulate in the brain during Alzheimer’s disease.
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A 2020 study of people with mild Alzheimer’s disease found that supplementation with 1 gram of lion’s mane mushroom daily for 49 weeks significantly improved cognitive test scores compared with a placebo .
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The ability of lion’s mane mushroom to promote nerve growth and protect the brain from Alzheimer’s-related damage may explain some of its beneficial effects on brain health.
However, it’s important to note that most of the research has been conducted on animals or in test tubes. Therefore, more human studies are needed.
SUMMARYLion’s mane mushrooms contain compounds that stimulate brain cell growth and protect them from damage caused by Alzheimer’s disease. However, more research involving humans is needed.
Up to one-third of people living in developed countries experience symptoms of anxiety and depression (8, 9).
While there are many causes of anxiety and depression, chronic inflammation could be a major contributing factor.
Animal research has found that lion’s mane mushroom extract has anti-inflammatory effects that can reduce symptoms of anxiety and depression in mice .
Other animal studies have found that lion’s mane extract can also help regenerate brain cells and improve the functioning of the hippocampus, a region of the brain that processes memories and emotional responses .
Researchers believe that improved hippocampus functioning may explain the reductions in anxious and depressive behaviors in mice receiving these extracts.
While these animal studies are promising, there is very little research involving humans.
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One small 2010 study of menopausal women found that eating cookies containing lion’s mane mushrooms daily for 1 month helped reduce self-reported feelings of irritation and anxiety .
The nervous system consists of the brain, spinal cord, and other nerves that travel throughout the body. These components work together to send and transmit signals that control almost every bodily function.
Brain or spinal cord injuries can cause various adverse medical outcomes. They often cause paralysis or loss of mental functions and can take a long time to heal.
However, research has found that lion’s mane mushroom extract may help speed recovery from these types of injuries by stimulating the growth and repair of nerve cells. Source, 16Trusted Source). It may also help reduce the severity of brain damage after a stroke.
However, no studies have been conducted involving humans to determine if lion’s mane would have the same therapeutic effect on nervous system injuries as animal research has suggested.
Ulcers can form anywhere along the digestive tract, including the stomach, small intestine, and large intestine.
Two major factors typically cause stomach ulcers: overgrowth of the bacteria H. pylori and damage to the mucous layer of the stomach that’s often due to long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) .
Lion’s mane extract may protect against the development of stomach ulcers by inhibiting the growth of H. pylori and protecting the stomach lining from damage
Several older studies have found that lion’s mane extract can prevent the growth of H. pylori in a test tube, but no studies have tested whether the extract has the same effects inside the stomach .
Another 2013 animal study found that lion’s mane extract was more effective at preventing alcohol-induced stomach ulcers than traditional acid-lowering drugs — and without any negative side effects .
Lion’s mane extract can also reduce inflammation and prevent tissue damage in other intestinal areas. In fact, they may help treat inflammatory bowel diseases like ulcerative colitis and Crohn’s disease .
A 2016 study of people with ulcerative colitis found that taking a mushroom supplement containing 14% lion’s mane extract significantly reduced symptoms and improved quality of life after 3 weeks .
However, when the same study was repeated in patients with Crohn’s disease, the benefits were roughly the same as with placebo .
It’s important to note that the herbal supplement used in these studies included several types of mushrooms, so it’s difficult to conclude about the effects of lion’s mane specifically.
Overall, research suggests that lion’s mane extract may help inhibit the development of ulcers, but more research involving humans is needed.
Research shows that lion’s mane extract can influence some of these factors and reduce the risk of heart disease.
Studies of rats and mice have found that lion’s mane mushroom extract improves fat metabolism and lowers triglyceride levels .
One 2010 study of rats fed a high fat diet and given daily doses of lion’s mane extract showed 27% lower triglyceride levels and 42% less weight gain after 28 days .
Since obesity and high triglycerides are both considered risk factors for heart disease, this is one way that lion’s mane mushrooms contribute to heart health.
Test-tube studies have also found that lion’s mane extract can help prevent the oxidation of cholesterol in the bloodstream .
Oxidized cholesterol molecules tend to attach to artery walls, causing them to harden and increase the risk of heart attack and stroke. Reducing oxidation is beneficial for heart health.
What’s more, lion’s mane mushrooms contain a compound called hericenone B, which can decrease the rate of blood clotting and lower the risk of heart attack or stroke .
Lion’s mane mushrooms appear to benefit the heart and blood vessels in multiple ways, but studies involving humans are needed to support this.
Diabetes is a disease that occurs when the body’s ability to manage blood sugar levels is impaired. As a result, levels are consistently elevated.
Chronically high blood sugar levels eventually cause complications like kidney disease, nerve damage in the hands and feet, and vision loss.
Lion’s mane mushroom may be beneficial for diabetes management by improving blood sugar management and reducing some of these side effects.
Several animal studies have shown that lion’s mane can cause significantly lower blood sugar levels in both normal and diabetic mice, even at daily dosages as low as 2.7 milligrams (mg) per pound (6 mg per kg) of body weight.
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One way that lion’s mane lowers blood sugars is by blocking the activity of the enzyme alpha-glucosidase, which breaks down carbs in the small intestine .
When this enzyme is blocked, the body is unable to digest and absorb carbs as effectively, which results in lower blood sugar levels.
In addition to lowering blood sugars, lion’s mane extract may reduce diabetic nerve pain in the hands and feet.
In mice with diabetic nerve damage, 6 weeks of daily lion’s mushroom extract significantly reduced pain, lowered blood sugar levels, and even increased antioxidant levels .
Lion’s mane mushroom shows potential as a therapeutic diabetes supplement, but more research is needed to determine exactly how it might be used in humans.
Cancer occurs when your DNA becomes damaged, causing your cells to divide and replicate out of control.
Some research suggests that lion’s mane mushroom has cancer-fighting abilities thanks to several of its unique compounds .
In fact, when lion’s mane extract is mixed with human cancer cells in a test tube, they cause the cancer cells to die faster. This has been demonstrated with several types of cancer cells, including liver, colon, stomach, and blood cancer cells (37Trusted Source, 38Trusted Source, 39Trusted Source, 40)Trusted Source. However, at least one older study has failed to replicate these results .
In addition to killing cancer cells, lion’s mane extract has also been shown to slow the spread of cancer.
One 2013 study of mice with colon cancer found that taking lion’s mane extract reduced the spread of cancer to the lungs by 69% .
Another 2014 study found that lion’s mane extract was more effective than traditional cancer medications at slowing tumor growth in mice, in addition to having fewer side effects .
However, the anticancer effects of lion’s mane mushroom have never been tested in humans, so more research is needed.
Chronic inflammation and oxidative stress are believed to be the root causes of many modern illnesses, including heart disease, cancer, and autoimmune disorders .
Research shows that lion’s mane mushrooms contain powerful anti-inflammatory and antioxidant compounds that may help reduce the impact of these illnesses .
In fact, a 2012 study examining the antioxidant abilities of 14 different mushroom species found that lion’s mane had the fourth highest antioxidant activity and recommended it be considered a good dietary source of antioxidants .
Several animal studies have found that lion’s mane extract reduced markers of inflammation and oxidative stress in rodents and may be especially useful in managing inflammatory bowel disease, liver damage, and stroke
Lion’s mane mushrooms may also help reduce some of the health risks associated with obesity, as they have been shown to decrease the amount of inflammation fat tissue releases .
More studies are needed to determine the potential health benefits in humans, but the results from lab and animal studies are promising.
A strong immune system protects the body from bacteria, viruses, and other disease-causing pathogens.
On the other hand, a weak immune system puts the body at a higher risk of developing infectious diseases.
Animal research shows that lion’s mane mushroom can boost immunity by increasing the activity of the intestinal immune system, which protects the body from pathogens that enter the gut through the mouth or nose .
These effects may partly be due to beneficial changes in gut bacteria that stimulate the immune system .
A 2012 study even found that supplementing with lion’s mane extract daily nearly quadrupled the lifespan of mice injected with a lethal dose of salmonella bacteria .
The immune-boosting effects of lion’s mane mushrooms are very promising, but this area of research is still developing.
There’s no standard dosage for lion’s mane mushrooms. The safest, most beneficial amount depends on factors like your age and overall health. You may want to talk with a doctor about the right dosage for you.
For improving cognition, some researchers recommend 3 to 5 grams per day.
In a 2020 study, people ages 50 and older with mild Alzheimer’s disease symptoms showed significantly improved cognitive function after taking three 350-mg lion’s mane capsules daily for 49 weeks. (
Taking three 400-mg capsules daily for 8 weeks helped relieve depression, anxiety, and sleep disorders for 77 people who were overweight or had obesity, according to a 2019 study.
Lion’s mane mushrooms can be enjoyed raw, cooked, dried, or steeped as tea.
Many people describe their flavor as “seafood-like,” often comparing it to crab or lobster .
The mushrooms can be cooked and served in dishes like risotto, pasta, or soup.
Lion’s mane mushroom powder can be mixed into hot water, tea, coffee, a smoothie, or other beverages. It can also be added to soup, stew, or gravy.
SUMMARYLion’s mane mushrooms can be eaten raw, cooked, or dried.
Fresh lion’s mane mushrooms have the greatest health benefits, according to some researchers. However, the cultivation methods may affect the mushrooms’ medicinal properties. (59)
Lion’s mane mushrooms are available over the counter in some of the following forms:
- tablets
- capsules
- powder
- tinctures
However, researchers advise that there are currently no guidelines to ensure these products are safe and effective.
SUMMARYAlthough fresh lion’s mane mushrooms may provide the most health benefits, they can also be taken as a supplement in forms like tablets or capsules.
No studies involving humans have examined the side effects of lion’s mane mushroom or its extract, but they appear to be very safe.
No adverse effects have been seen in rats, even at doses as high as 2.3 grams per pound (5 grams per kg) of body weight per day for 1 month or lower dosages for 3 months .
However, anyone who is allergic or sensitive to mushrooms should avoid lion’s mane since it’s a mushroom species.
There have been documented cases of people experiencing difficulty breathing or skin rashes after exposure to lion’s mane mushrooms, likely related to allergies.
What Is Lion’s Mane Mushroom?
Lion’s mane is a mushroom with a history of both medicinal and culinary uses in Asia and Europe. Medicinal mushroom use dates back to 450 BCE when Greek physician Hippocrates discovered the potential anti-inflammatory properties of fungi as well as its role in wound cauterization, according to a 2017 study in the Journal of Restorative Medicine[1].
Lion’s mane grows on old or dead broadleaf tree trunks. Broadleaf trees shed their leaves seasonally and spread their seeds using a vessel, such as fruit.
Lion’s mane is composed of two parts: the visible fruiting body (the mushroom) and the mycelium, which is the bottom structure that resembles roots. Both the fruiting body and the root-like mycelium contain compounds that offer potential health benefits.
Lion’s Mane Health Benefits
The potential benefits of lion’s mane mushroom are numerous and span physical, cognitive and mental health[2]. The mushroom is a source of natural bioactive compounds, which are health-promoting chemicals found in certain foods and plants. As a result, it exhibits disease-fighting properties, including anti-cancer, anti-microbial and antioxidant activity.
Research also suggests that lion’s mane may protect nerves from disease or decline, according to a 2015 abstract in the Journal of Agricultural and Food Chemistry. The same study concludes the mushroom displays additional health-promoting benefits, such as:
- Regulates blood sugar
- Reduces high blood pressure
- Promotes healthy energy levels and combats fatigue
- Helps to prevent excess blood lipid accumulation
- Protects heart health
- Slows biological aging
- Protects liver health
- Protects kidney health
Potential Alternative Treatment for Depression
Lion’s mane mushroom may be a potential alternative treatment for depression, according to a 2020 abstract in the Journal of Molecular Science. The abstract highlights three ways in which lion’s mane may ease depression symptoms:
- Helping ensure the presence of sufficient neurotransmitters
- Reducing the loss of nerve growth brought about by stressful situations
- Minimizing inflammation linked to depression[3].
Furthermore, research shows that people living with major depressive disorder may have lower nerve growth factor than non-depressed people, according to a 2015 meta-analysis in Neuropsychiatric Disease and Treatment[4]. Nerve growth factor helps nerve cells specialize, grow and remain healthy, which are important aspects of mood regulation.
A number of studies demonstrate that lion’s mane increases nerve growth factor, according to Lexi Watson, a doctor of pharmacology, functional medicine practitioner and founder of Oakley Wellness, a practice that specializes in brain health and optimal aging.
May Benefit Brain Health
Lion’s mane’s effect on nerve growth factor levels may enable it to help protect against disorders like Alzheimer’s disease that feature cognitive impairment.
Lion’s mane is a type of nootropic, meaning it contains compounds that improve brain health and function, according to Best.
“Some research has shown a benefit on certain measures of memory and cognitive function,” says Tod Cooperman, M.D., a dietary supplement researcher and president and founder of ConsumerLab.com, a health and nutrition product testing company. “But results have been inconsistent, and most improvements have been modest at best,” he adds.
For example, lion’s mane may be effective at improving symptoms of mild cognitive impairment, according to a placebo-controlled trial in Phytotherapy Research. In the trial, adults ages 50 to 80 took four 250-milligram powdered lion’s mane tablets three times daily for 16 weeks. Cognitive function scale testing showed that participants taking lion’s mane scored higher than the placebo group, and their cognitive ability improved with the duration of supplementation. Four weeks after discontinuing lion’s mane, their cognitive test scores decreased[5].
Promotes Brain Injury Recovery
A 2021 study in Antioxidants offers some promising research of lion’s mane for people who’ve experienced traumatic brain injury (TBI). The study found that both lion’s mane mushroom and coriolus versicolor (another type of mushroom also known as turkey tail) exhibit neuroprotective effects against the inflammation and oxidative stress often associated with TBI[6].
The neurodegeneration, or progressive breakdown of nerve cells, caused by TBI can lead to further conditions like Parkinson’s disease. Treatment with lion’s mane may reduce the impact of brain trauma and TBI complications like Parkinson’s disease.
Reduces Anxiety and Stress
Lion’s mane may help ease stress, according to Best, and a 2010 study in Biomedical Research provides some evidence to support this theory. The study examines the effects of lion’s mane on brain function and concludes that participants who ate cookies containing 0.5 grams of powdered lion’s mane (specifically the mushroom or fruiting body) for four weeks reported less anxiety than those who ate placebo cookies. The study authors theorize that the nerve growth effect of lion’s mane mushroom contributes to its anti-anxiety action.
Supports Gastrointestinal Health
Lion’s mane mushroom exhibits ulcer-inhibiting action, which research suggests may stem from its effect on the helicobacter pylori (H. pylori) bacteria. H. pylori can cause stomach issues including ulcers, according to a study in the Journal of Ethnopharmacology[7].
Does Lion’s Mane Have Side Effects?
If you have a medical condition or a history of asthma or allergies, consult your doctor before you try lion’s mane.
“Lion’s mane is generally well tolerated, but the most common side effects include gastrointestinal discomfort, nausea and a skin rash,” says Dr. Watson.
If you experience side effects, discontinue lion’s mane consumption until you’ve spoken with a health care provider. Hives, swelling, diarrhea and abdominal pain were symptoms of a potentially serious allergic reaction to lion’s mane mushroom, according to a 2022 case study in Annals of Allergy, Asthma & Immunology.
How to Use Lion’s Mane
Lion’s mane mushroom can be taken as a supplement form, such as in capsules or a powder, or used fresh as a culinary ingredient. When used for culinary purposes, lion’s mane mushroom has a mild flavor that allows it to blend with a variety of meals and may be used as a plant-based meat substitute or a supplemental powder stirred into coffee or tea.
Lion’s mane powder is also used in savory dishes like stew, or sweet beverages like hot chocolate. It can also be made into a tea by adding hot water to mushroom pieces or powder.
Lion’s Mane Dosage
As with any supplement, it’s important to take lion’s mane as directed by the manufacturer’s instructions and not to exceed the recommended dose unless directed to do so by a health care provider.
“Most studies have provided [participants with] about 1 gram of dried mushroom (although some have used mycelium [root-like structure] or a combination of the two [mycelium and fruiting body]) given three times daily,” says Dr. Cooperman
Dr. Watson takes a more conservative approach, recommending 250 to 500 milligrams up to three times a day with or without food. The brand she recommends, Om Organic Mushroom Nutrition, contains both mycelial biomass and the fruit body.
Avoid taking lion’s mane during pregnancy and lactation since there’s insufficient research to determine its safety. As with any supplement, speak to your health care provider to determine if lion’s mane is right for you and to determine the proper dosage for your health needs.
What to Look for When Purchasing Lion’s Mane
When purchasing lion’s mane, Dr. Cooperman recommends reading labels carefully. “Be aware that most research has focused on the portion of lion’s mane that grows above ground (the mushroom) as opposed to the part underground (the mycelium),” he says. “In our tests, we found that two out of eight lion’s mane products claim to be [made from the] mushroom but are actually mycelium, as confirmed in our testing. So a consumer needs to be sure they are getting a product that contains what they are expecting.”
Dr. Watson advises assessing the manufacturer when you’re considering a lion’s mane supplement. “I recommend taking lion’s mane from manufacturers who provide professional-grade supplements,” she says. “These companies work hard to ensure they use the best ingredients from the best sources and follow up their products with third-party testing. This ensures that what you put in your body is high quality, matches what it says on the label and will have the best chance of working for you,” she adds.
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